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Figure 4 | BMC Bioinformatics

Figure 4

From: Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data

Figure 4

Pearson correlation coefficients of PPI pairs and corresponding Gene-Gene Interaction GGI pairs. 1,037 interacting protein pairs from the HPRD were analyzed based on the GEO dataset GDS987. A) Distributions of PCC values for PPI pairs, GGI pairs and random pairs. The two arrows indicate the regions where expression correlations were strengthened by the PPI PCC calculation. (B) Scatter plot of PCC values of PPI pairs vs. those of corresponding GGI pairs. X-axis indicates the PCC values of PPI pairs, and y-axis indicates the PCC values of the corresponding GGI pairs. A linear regression resulted in a regression line and a regression formula, which were shown in green. Totals within each quadrants were marked with black numbers at the four corners.

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