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Table 2 Thresholds of three different algorithms to infer haplotype block

From: Evaluation of sample size effect on the identification of haplotype blocks

 

Algorithms

Thresholds

1

Four-gametes test (recombination-based)

Threshold of forth gamete's haplotype frequency: 0.01

2

Gabriel's method (LD-based)

Confidence interval threshold for strong LD (lower side): 0.70

Confidence interval threshold for strong LD (upper side): 0.98

Upper confidence interval maximum for strong recombination: 0.90

Threshold of strong LD rate in region: 0.95

3

Kamatani's method (diversity-based)

Threshold of |D'| for initial clustering: 0.90

Threshold of haplotype frequency adding neighboring SNPs: 0.01