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Table 4 Accuracy and time comparison of the algorithms on four real datasets involving different numbers of genotypes

From: ISHAPE: new rapid and accurate software for haplotyping

 

ACE

APOE

GH1

Chr 5q31

 

11 genotypes

80 genotypes

153 genotypes

258 genotypes

Prog

SER

Time (sec.)

SER

Time (sec.)

SER

Time (sec.)

SER

Time (sec.)

Ishape1

0.0190 +/- 0.002

0.8

0.055 +/- 0.001

0.2

0.065 +/- 0.003

0.9

0.0473 +/- 0.001

512

Ishape2

0.0184 +/- 0.0006

4.96

0.050 +/- 0.005

3.5

0.052 +/- 0.004

9.2

0.0451 +/- 0.001

5744

Phase1.0

0.0186 +/- 0.001

4.82

0.055 +/- 0.001

2.7

0.065 +/- 0.004

15.6

0.0657 +/- 0.002

21536

Phase2.1

0.0175 +/- 0.000

23.25

0.049 +/- 0.005

14

0.052 +/- 0.003

62.9

0.0501 +/- 0.001

61789

fastPhase

0.0182 +/- 0.001

37.61

0.103 +/- 0.009

49.1

0.056 +/- 0.003

139.1

0.0452 +/- 0.001

986

PL-EM

0.0573 +/- 0.005

0.51

0.165 +/- 0.000

0.11

0.060 +/- 0.004

0.31

0.0601 +/- 0.001

6507

2snp

0.0116 +/- 0.000

<0.1

0.230 +/- 0.000

< 0.1

0.074 +/- 0.000

< 0.1

0.0513 +/- 0.000

3

  1. Accuracy and time comparison of the algorithms on the four real datasets ACE [29], APOE [36], GH1 [20,35] genes and data from Chr. 5q31 [30]. The 95% confidence interval corresponds to 100 runs of each program for ACE, APOE and ACE, and to 10 runs for Chr.5q31 data. Best performances are highlighted in bold.