Yeast network modules and protein biosynthesis genes for different GTOM m. A. The adjacency matrix (GTOM0). B. Standard Ravasz et al.'s TOM (GTOM1). C. Our new generalized TOM (GTOM2). In each column, the top row shows the dendrogram obtained by applying the average linkage hierarchical clustering to the corresponding GTOM dissimilarity, the middle row shows the color bar ordered by the corresponding dendrogram but colored by the module assignment with respect to the TOM measure in B, the bottom shows the color bar ordered by the corresponding dendrogram but colored in dark red if the gene belongs to the class 'protein biosynthesis'. The modules defined by the TOM are the branches of the dendrogram in B at the cutoff 0.95. Almost all protein biosynthesis genes are grouped together by the proposed new TOM measure whereas the other two measures tend to distribute the class over two modules. The modules defined by GTOM2 are more pronounced in the sense that they are separated by larger distances.