Table 1 Predicted clusters of readthrough proteins
From: Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach
Cluster description | Codon | Size | Example organism (locus) |
|---|---|---|---|
Selenocysteine | Â | Â | Â |
Formate dehydrogenase α subunit | TGA | 45 | Escherichia coli (b1474) |
Selenide water dikinase | TGA | 12 | Haemophilus influenzae (HI0200m) |
Glycine reductase complex selenoprotein A | TGA | 6 | Treponema denticola (TDE0745) |
Glycine reductase complex selenoprotein B | TGA | 6 | Treponema denticola (TDE0078) |
Heterodisulfide reductase subunit A | TGA | 6 | Methanococcus jannaschii (MJ1190m) |
Coenzyme F420-reducing hydrogenase δ subunit | TGA | 5 | Methanococcus jannaschii (MJ1190a) |
Formylmethanofuran dehydrogenase subunit B | TGA | 4 | Methanococcus jannaschii (MJ1194m) |
Glutaredoxin-like | TGA | 3 | Carboxydothermus hydrogenoformans (CHY_0740) |
Thioredoxin | TGA | 3 | Geobacter sulfurreducens (GSU3446) |
Coenzyme F420-reducing hydrogenase α subunit | TGA | 3 | Methanococcus jannaschii (MJ0029) |
HesB family | TGA | 3 | Desulfovibrio vulgaris (DVU_1382) |
HesB family | TGA | 2 | Methanococcus maripaludis (MMP0252 + upstream) |
Fe-S oxidoreductase | TGA | 2 | Desulfotalea psychrophila (DP1009) |
DsbA-like | TGA | 2 | Desulfovibrio desulfuricans (Dde_1263 + upstream) |
Periplasmic [NiFeSe] hydrogenase large subunit | TGA | 2 | Desulfovibrio vulgaris (DVU_1918) |
Pyrrolysine | Â | Â | Â |
Monomethylamine methyltransferase | TAG | 7 | Methanosarcina acetivorans (MA0144) |
Dimethylamine methyltransferase | TAG | 7 | Methanosarcina acetivorans (MA0532) |
Trimethylamine methyltransferase | TAG | 6 | Methanosarcina acetivorans (MA0528) |
Transcriptional regulator, TetR family | TAG | 2 | Methanosarcina acetivorans (MA2902) |
Unknown | Â | Â | Â |
Cytochrome c family protein | TGA | 2 | Geobacter sulfurreducens (GSU2937 + GSU2936) |
Hypothetical protein | TAG | 2 | Geobacter sulfurreducens (GSU2293 + downstream) |