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Table 2 Identified interactions among subset of genes in B. anthracis

From: A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression data

 

spo0F/ Spo0A~P

sigF

sigE

spoIIIJ

sigG

spoIVFB

spoIIID

sigK

gerE

spo0F/Spo0A~P

0

0

0

*

0

0

-1

0

1

SigF

1

0

0

0

0

*

-1

0

0

SigE

0

1

0

*

*

0

*

0

0

SpoIIIJ

1

0

0

0

*

0

*

*

0

SigG

-1

0

1

0

0

0

0

0

*

spoIVFB

*

0

1

0

0

0

*

-1

0

SpoIIID

-1

1

1

0

0

0

0

0

0

SigK

*

0

0

*

0

1

0

1

0

GerE

0

0

0

0

-1

-1

0

1

0

  1. Identified interactions obtained from the inference method for the set of 9 genes involved in the sporulation cascade on B. anthracis. '1' indicates an activating interaction, '-1' an inhibiting interaction, '0' an absent interaction and '*' an interaction for which a conclusion could not be drawn. A row corresponds to a regulated gene and a column corresponds to a regulator gene. For example, sigE positively regulates sigG, spoIVFB and spoIIID.