Skip to main content
Figure 6 | BMC Bioinformatics

Figure 6

From: A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance

Figure 6

Comparison between sam2.20 and the symmetric cutoff method under setup 3(iv). The histogram and the parallel boxplots in Figure 6 are defined the same as in Figure 4. It is clear from the histogram that sam2.20 tends to produce significantly higher number of true FP than the symmetric cutoff method. The parallel boxplots show that both methods over-estimate the true FDR. It can also been seen that the over-estimation for the symmetric cutoff method is more serious than that of sam2.20. The second and fourth boxplots at the right of Figure 6 show that the over-estimation has been corrected by FP correction (12) for both methods.

Back to article page