TY - JOUR AU - Hart, G. Traver AU - Lee, Insuk AU - Marcotte, Edward M. PY - 2007 DA - 2007/07/02 TI - A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality JO - BMC Bioinformatics SP - 236 VL - 8 IS - 1 AB - Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purification-mass spectrometry (TAP-MS) assays in yeast have been published, along with corresponding complex maps. For most complexes, the published data sets were surprisingly uncorrelated. It is therefore useful to consider the raw data from each study and generate an accurate complex map from a high-confidence data set that integrates the results of these and earlier assays. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-8-236 DO - 10.1186/1471-2105-8-236 ID - Hart2007 ER -