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Table 5 Validated orphan activities

From: A survey of orphan enzyme activities

EC No. Ranking EC No. Ranking EC No. Ranking
1.1.1.13 difficult 1.14.99.24 difficult 3.1.3.47 good
1.1.1.16 difficult 1.21.3.2 difficult 3.1.3.59 difficult
1.1.1.43 difficult 1.97.1.3 difficult 3.1.3.72 difficult
1.1.1.54 difficult 2.1.1.112 difficult 3.1.4.43 difficult
1.1.1.84 excellent 2.1.1.137 artifact 3.1.6.17 good
1.1.1.92 marginal 2.1.1.141 artifact 3.1.8.2 artifact
1.1.1.101 difficult 2.1.1.143 artifact 3.2.1.56 difficult
1.1.1.144 difficult 2.1.1.147 difficult 3.2.1.77 difficult
1.1.1.146 artifact 2.1.1.84 difficult 3.2.1.100 good
1.1.1.163 artifact 2.1.1.99 difficult 3.2.1.112 excellent
1.1.1.172 good 2.1.2.4 difficult 3.2.1.115 difficult
1.1.1.196 good 2.3.1.14 difficult 3.2.1.128 excellent
1.1.1.208 poor 2.3.1.23 difficult 3.2.1.136 difficult
1.1.1.226 excellent 2.3.1.24 artifact 3.2.1.137 poor
1.1.1.245 artifact 2.3.1.33 difficult 3.2.2.10 difficult
1.1.1.258 artifact 2.3.1.49 difficult 3.4.11.16 good
1.1.1.265 excellent 2.3.1.68 marginal 3.4.13.7 difficult
1.1.2.5 artifact 2.3.1.96 difficult 3.4.17.16 good
1.1.3.23 difficult 2.3.1.98 good 3.4.21.103 artifact
1.17.1.1 difficult 2.3.1.102 artifact 3.4.22.44 artifact
1.17.99.2 artifact 2.3.1.103 poor 3.4.22.46 artifact
1.2.1.18 artifact 2.3.1.105 poor 3.4.23.28 difficult
1.2.1.20 difficult 2.3.1.114 poor 3.4.23.30 artifact
1.2.1.23 poor 2.3.1.133 marginal 3.4.24.54 artifact
1.2.1.25 difficult 2.3.1.140 difficult 3.5.1.30 good
1.2.1.32 artifact 2.3.1.161 artifact 3.5.1.33 artifact
1.2.1.33 difficult 2.3.2.3 artifact 3.5.1.39 poor
1.2.1.52 difficult 2.3.2.7 difficult 3.5.1.58 excellent
1.2.1.54 good 2.3.3.3 difficult 3.5.1.62 artifact
1.2.1.63 marginal 2.4.1.23 poor 3.5.1.67 difficult
1.2.1.64 artifact 2.4.1.29 difficult 3.5.1.71 poor
1.2.3.6 difficult 2.4.1.41 valid 3.5.1.79 artifact
1.2.3.7 poor 2.4.1.43 difficult 3.5.2.13 poor
1.2.3.8 artifact 2.4.1.57 artifact 3.5.2.16 artifact
1.3.1.4 difficult 2.4.1.66 artifact 3.5.3.2 good
1.3.1.5 difficult 2.4.1.73 artifact 3.5.5.2 difficult
1.3.1.6 artifact 2.4.1.97 difficult 3.6.1.18 excellent
1.3.1.11 difficult 2.4.1.110 poor 3.6.1.2 artifact
1.3.1.37 difficult 2.4.1.125 difficult 3.6.1.52 artifact
1.3.7.1 difficult 2.4.1.126 valid 3.6.3.17 artifact
1.3.99.15 artifact 2.4.1.153 poor 3.6.3.24 artifact
1.3.99.21 artifact 2.4.1.167 difficult 3.6.3.28 artifact
1.4.1.11 good 2.4.1.176 difficult 3.6.4.4 artifact
1.4.1.17 good 2.4.1.180 excellent 4.1.1.24 difficult
1.4.99.4 marginal 2.4.1.184 difficult 4.1.1.52 difficult
1.4.99.5 artifact 2.4.1.215 artifact 4.1.1.56 difficult
1.5.1.21 good 2.4.2.35 difficult 4.1.1.75 difficult
1.5.99.11 artifact 2.5.1.4 difficult 4.1.2.23 difficult
1.6.5.7 artifact 2.5.1.42 difficult 4.1.2.28 difficult
1.7.3.1 difficult 2.6.1.22 difficult 4.1.2.35 difficult
1.7.3.5 valid 2.6.1.27 poor 4.1.3.35 difficult
1.8.1.5 artifact 2.6.1.32 difficult 4.2.1.5 difficult
1.10.1.1 difficult 2.6.1.33 poor 4.2.1.43 good
1.10.3.4 difficult 2.6.1.75 good 4.2.1.62 good
1.12.98.2 artifact 2.7.1.43 difficult 4.2.1.77 difficult
1.13.11.14 difficult 2.7.1.54 difficult 4.2.1.81 difficult
1.13.11.24 artifact 2.7.1.64 difficult 4.2.1.93 difficult
1.13.11.25 artifact 2.7.1.77 difficult 4.2.1.97 marginal
1.13.11.35 difficult 2.7.1.106 difficult 4.2.1.101 artifact
1.13.12.9 good 2.7.1.131 poor 4.2.2.14 artifact
1.14.11.10 difficult 2.7.1.134 difficult 4.2.3.19 artifact
1.14.11.6 poor 2.7.1.142 difficult 4.2.99.19 artifact
1.14.13.10 marginal 2.7.4.20 difficult 4.3.1.10 difficult
1.14.13.23 good 2.7.7.44 difficult 4.3.1.20 difficult
1.14.13.24 artifact 2.7.7.51 difficult 4.5.1.4 difficult
1.14.13.42 difficult 2.7.8.10 difficult 5.1.1.6 difficult
1.14.13.51 difficult 2.7.8.22 difficult 5.1.1.9 marginal
1.14.13.58 excellent 2.8.1.3 excellent 5.1.3.17 difficult
1.14.13.60 difficult 2.8.2.28 difficult 5.2.1.10 difficult
1.14.13.72 difficult 3.1.1.36 difficult 5.2.1.11 difficult
1.14.13.73 artifact 3.1.1.39 difficult 5.4.3.5 artifact
1.14.15.2 difficult 3.1.1.40 poor 5.5.1.11 good
1.14.16.5 good 3.1.1.78 artifact 5.5.1.12 artifact
1.14.99.18 artifact 3.1.2.11 difficult 5.5.1.3 difficult
1.14.99.22 artifact 3.1.3.14 difficult 6.3.1.6 difficult
   3.1.3.38 poor 6.3.4.8 difficult
  1. All 228 orphans reviewed in this study are listed. The salvageability of an orphan is ranked "difficult" when factors such as unclear species of origin, lack of molecular descriptors, or lack of comprehensive genome sequence hinder cloning of the cognate gene. Note that such rankings do not take into account the availability of molecular descriptors which enable the identification of a candidate gene in one species, and, through orthology, the identification of a candidate gene in a second species for which these descriptors are not available.