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Table 5 Validated orphan activities

From: A survey of orphan enzyme activities

EC No.

Ranking

EC No.

Ranking

EC No.

Ranking

1.1.1.13

difficult

1.14.99.24

difficult

3.1.3.47

good

1.1.1.16

difficult

1.21.3.2

difficult

3.1.3.59

difficult

1.1.1.43

difficult

1.97.1.3

difficult

3.1.3.72

difficult

1.1.1.54

difficult

2.1.1.112

difficult

3.1.4.43

difficult

1.1.1.84

excellent

2.1.1.137

artifact

3.1.6.17

good

1.1.1.92

marginal

2.1.1.141

artifact

3.1.8.2

artifact

1.1.1.101

difficult

2.1.1.143

artifact

3.2.1.56

difficult

1.1.1.144

difficult

2.1.1.147

difficult

3.2.1.77

difficult

1.1.1.146

artifact

2.1.1.84

difficult

3.2.1.100

good

1.1.1.163

artifact

2.1.1.99

difficult

3.2.1.112

excellent

1.1.1.172

good

2.1.2.4

difficult

3.2.1.115

difficult

1.1.1.196

good

2.3.1.14

difficult

3.2.1.128

excellent

1.1.1.208

poor

2.3.1.23

difficult

3.2.1.136

difficult

1.1.1.226

excellent

2.3.1.24

artifact

3.2.1.137

poor

1.1.1.245

artifact

2.3.1.33

difficult

3.2.2.10

difficult

1.1.1.258

artifact

2.3.1.49

difficult

3.4.11.16

good

1.1.1.265

excellent

2.3.1.68

marginal

3.4.13.7

difficult

1.1.2.5

artifact

2.3.1.96

difficult

3.4.17.16

good

1.1.3.23

difficult

2.3.1.98

good

3.4.21.103

artifact

1.17.1.1

difficult

2.3.1.102

artifact

3.4.22.44

artifact

1.17.99.2

artifact

2.3.1.103

poor

3.4.22.46

artifact

1.2.1.18

artifact

2.3.1.105

poor

3.4.23.28

difficult

1.2.1.20

difficult

2.3.1.114

poor

3.4.23.30

artifact

1.2.1.23

poor

2.3.1.133

marginal

3.4.24.54

artifact

1.2.1.25

difficult

2.3.1.140

difficult

3.5.1.30

good

1.2.1.32

artifact

2.3.1.161

artifact

3.5.1.33

artifact

1.2.1.33

difficult

2.3.2.3

artifact

3.5.1.39

poor

1.2.1.52

difficult

2.3.2.7

difficult

3.5.1.58

excellent

1.2.1.54

good

2.3.3.3

difficult

3.5.1.62

artifact

1.2.1.63

marginal

2.4.1.23

poor

3.5.1.67

difficult

1.2.1.64

artifact

2.4.1.29

difficult

3.5.1.71

poor

1.2.3.6

difficult

2.4.1.41

valid

3.5.1.79

artifact

1.2.3.7

poor

2.4.1.43

difficult

3.5.2.13

poor

1.2.3.8

artifact

2.4.1.57

artifact

3.5.2.16

artifact

1.3.1.4

difficult

2.4.1.66

artifact

3.5.3.2

good

1.3.1.5

difficult

2.4.1.73

artifact

3.5.5.2

difficult

1.3.1.6

artifact

2.4.1.97

difficult

3.6.1.18

excellent

1.3.1.11

difficult

2.4.1.110

poor

3.6.1.2

artifact

1.3.1.37

difficult

2.4.1.125

difficult

3.6.1.52

artifact

1.3.7.1

difficult

2.4.1.126

valid

3.6.3.17

artifact

1.3.99.15

artifact

2.4.1.153

poor

3.6.3.24

artifact

1.3.99.21

artifact

2.4.1.167

difficult

3.6.3.28

artifact

1.4.1.11

good

2.4.1.176

difficult

3.6.4.4

artifact

1.4.1.17

good

2.4.1.180

excellent

4.1.1.24

difficult

1.4.99.4

marginal

2.4.1.184

difficult

4.1.1.52

difficult

1.4.99.5

artifact

2.4.1.215

artifact

4.1.1.56

difficult

1.5.1.21

good

2.4.2.35

difficult

4.1.1.75

difficult

1.5.99.11

artifact

2.5.1.4

difficult

4.1.2.23

difficult

1.6.5.7

artifact

2.5.1.42

difficult

4.1.2.28

difficult

1.7.3.1

difficult

2.6.1.22

difficult

4.1.2.35

difficult

1.7.3.5

valid

2.6.1.27

poor

4.1.3.35

difficult

1.8.1.5

artifact

2.6.1.32

difficult

4.2.1.5

difficult

1.10.1.1

difficult

2.6.1.33

poor

4.2.1.43

good

1.10.3.4

difficult

2.6.1.75

good

4.2.1.62

good

1.12.98.2

artifact

2.7.1.43

difficult

4.2.1.77

difficult

1.13.11.14

difficult

2.7.1.54

difficult

4.2.1.81

difficult

1.13.11.24

artifact

2.7.1.64

difficult

4.2.1.93

difficult

1.13.11.25

artifact

2.7.1.77

difficult

4.2.1.97

marginal

1.13.11.35

difficult

2.7.1.106

difficult

4.2.1.101

artifact

1.13.12.9

good

2.7.1.131

poor

4.2.2.14

artifact

1.14.11.10

difficult

2.7.1.134

difficult

4.2.3.19

artifact

1.14.11.6

poor

2.7.1.142

difficult

4.2.99.19

artifact

1.14.13.10

marginal

2.7.4.20

difficult

4.3.1.10

difficult

1.14.13.23

good

2.7.7.44

difficult

4.3.1.20

difficult

1.14.13.24

artifact

2.7.7.51

difficult

4.5.1.4

difficult

1.14.13.42

difficult

2.7.8.10

difficult

5.1.1.6

difficult

1.14.13.51

difficult

2.7.8.22

difficult

5.1.1.9

marginal

1.14.13.58

excellent

2.8.1.3

excellent

5.1.3.17

difficult

1.14.13.60

difficult

2.8.2.28

difficult

5.2.1.10

difficult

1.14.13.72

difficult

3.1.1.36

difficult

5.2.1.11

difficult

1.14.13.73

artifact

3.1.1.39

difficult

5.4.3.5

artifact

1.14.15.2

difficult

3.1.1.40

poor

5.5.1.11

good

1.14.16.5

good

3.1.1.78

artifact

5.5.1.12

artifact

1.14.99.18

artifact

3.1.2.11

difficult

5.5.1.3

difficult

1.14.99.22

artifact

3.1.3.14

difficult

6.3.1.6

difficult

  

3.1.3.38

poor

6.3.4.8

difficult

  1. All 228 orphans reviewed in this study are listed. The salvageability of an orphan is ranked "difficult" when factors such as unclear species of origin, lack of molecular descriptors, or lack of comprehensive genome sequence hinder cloning of the cognate gene. Note that such rankings do not take into account the availability of molecular descriptors which enable the identification of a candidate gene in one species, and, through orthology, the identification of a candidate gene in a second species for which these descriptors are not available.