3.4.21.103
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Physarolisin (a proteinase)
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Physarum flavicomum
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1982
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Q8MZS4
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IUBMB entry lists a 2003 paper describing a gene coding for a protein with this activity [28]. Sequence is in Swiss-Prot but ENZYME does not reference this sequence.
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Lack of database cross-referencing presumably involving the long interval between the initial characterization of the activity and the cloning of the gene.
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3.5.2.16
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Maleimide hydrolase
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Blastobacter sp. A17p-4
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1997
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Q93T25
|
ENZYME and IUBMB entries are not referencing a Swiss-Prot entry from a 2002 paper describing the cloning of gene coding for this [29].
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Lack of database cross-referencing is not restricted to older orphans.
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3.5.1.79
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Phthalyl amidase
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Xanthobacter agilis
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1995
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N/A
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The sequence, listed in a patent associated with a 1996 paper by [30] in Journal of Molecular Catalysis B: Enzymatic are available from Entrez, but not from TrEMBL. The paper itself is not available from PubMed.
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Note: though the protein sequence is not available from the UniProt database, the DNA sequence is present in the EMBL database.
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3.1.8.2
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Diisopropyl-fluoro-phosphatase
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Alteromonas sp.
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1954
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Q44238
|
ENZYME and IUBMB entries are not referencing a Swiss-Prot entry associated with a 1996 paper describing the cloning of a gene coding for an enzyme with this activity [31].
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This enzymatic activity detoxifies nerve gas. The gene is part of a widespread gene family with otherwise unknown function, with members in Homo sapiens.
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