|
3.4.21.103
|
Physarolisin (a proteinase)
|
Physarum flavicomum
|
1982
|
Q8MZS4
|
IUBMB entry lists a 2003 paper describing a gene coding for a protein with this activity [28]. Sequence is in Swiss-Prot but ENZYME does not reference this sequence.
|
Lack of database cross-referencing presumably involving the long interval between the initial characterization of the activity and the cloning of the gene.
|
|
3.5.2.16
|
Maleimide hydrolase
|
Blastobacter sp. A17p-4
|
1997
|
Q93T25
|
ENZYME and IUBMB entries are not referencing a Swiss-Prot entry from a 2002 paper describing the cloning of gene coding for this [29].
|
Lack of database cross-referencing is not restricted to older orphans.
|
|
3.5.1.79
|
Phthalyl amidase
|
Xanthobacter agilis
|
1995
|
N/A
|
The sequence, listed in a patent associated with a 1996 paper by [30] in Journal of Molecular Catalysis B: Enzymatic are available from Entrez, but not from TrEMBL. The paper itself is not available from PubMed.
|
Note: though the protein sequence is not available from the UniProt database, the DNA sequence is present in the EMBL database.
|
|
3.1.8.2
|
Diisopropyl-fluoro-phosphatase
|
Alteromonas sp.
|
1954
|
Q44238
|
ENZYME and IUBMB entries are not referencing a Swiss-Prot entry associated with a 1996 paper describing the cloning of a gene coding for an enzyme with this activity [31].
|
This enzymatic activity detoxifies nerve gas. The gene is part of a widespread gene family with otherwise unknown function, with members in Homo sapiens.
|
