From: Artificial neural network models for prediction of intestinal permeability of oligopeptides
 |  |  |  | Hydrophobicity* |  | |||
---|---|---|---|---|---|---|---|---|
Amino acid | Hominga | Randomb | Ratioc | Calculatedd | Side-chain analoguese | Amino acidsf | N-acetyl amidesg | Hydrophilicity* |
Alanine | 6.85 | 6.50 | 1.05 | -0.39 | -0.87 | -0.50 | -0.31 | -0.45 |
Glycine | 4.02 | 2.20 | 1.83 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
Isoleucine | 1.56 | 2.10 | 0.74 | -1.82 | -3.98 | -1.80 | -1.80 | -0.24 |
Leucine | 7.19 | 9.60 | 0.75 | -1.82 | -3.98 | -1.80 | -1.70 | -0.11 |
Valine | 1.98 | 1.90 | 1.04 | -1.30 | -3.10 | -1.50 | -1.22 | -0.40 |
Methionine | 2.69 | 3.30 | 0.82 | -0.96 | -1.41 | -1.30 | -1.23 | -3.87 |
Phenylalanine | 1.56 | 2.10 | 0.74 | -2.27 | -2.04 | -2.50 | -1.79 | -3.15 |
Tryptophan | 0.66 | 1.90 | 0.35 | -2.13 | -1.39 | -3.40 | -2.25 | -8.27 |
Proline | 11.41 | 10.70 | 1.07 | -0.99 | - | -1.40 | -0.72 | - |
Cysteine | 0.02 | 0.00 | - | -0.99 | -0.34 | -1.00 | -1.54 | -3.63 |
Serine | 13.42 | 8.60 | 1.56 | 1.24 | 4.34 | 0.30 | 0.04 | -7.45 |
Threonine | 10.72 | 13.10 | 0.82 | 1.00 | 3.51 | -0.40 | -0.26 | -7.27 |
Tyrosine | 1.95 | 2.40 | 0.81 | -1.47 | 1.08 | -2.30 | -0.96 | -8.50 |
Asparagine | 6.22 | 6.40 | 0.97 | 1.91 | 7.58 | 0.20 | 0.60 | -12.07 |
Glutamine | 7.56 | 7.10 | 1.06 | 1.30 | 6.48 | 0.20 | 0.22 | -11.77 |
Histidine | 6.74 | 6.90 | 0.98 | 0.64 | 5.60 | -0.50 | -0.13 | -12.66 |
Lysine | 5.33 | 3.80 | 1.40 | 2.77 | 6.49 | 3.00 | 0.99 | -11.91 |
Arginine | 4.89 | 4.30 | 1.14 | 3.95 | 15.86 | 3.00 | 1.01 | -22.31 |
Aspartic acid | 3.06 | 4.10 | 0.75 | 3.81 | 9.66 | 2.50 | 0.77 | -13.34 |
Glutamic acid | 2.18 | 3.10 | 0.70 | 2.91 | 7.75 | 2.50 | 0.64 | -12.63 |
Correlation Coefficienth | 0.17 | 0.21 | 0.40 | 0.50 | 0.03 |