Reuse of structural domain–domain interactions in protein networks

BMC Bioinformatics

Table 3 Prediction of total number of iPfam domain pairs

Species	Θ_S	θ _S	Ψ_S	ψ _S	χ _S	${\hat{x}}_{S}$	Ξ	ξ _S	$\hat{x}$
E. coli	1281	211	4314	1163	347	7814	8957	2070	33813
S. cerevisiae	45707	2045	5780	5359	835	20129	8957	2119	85085
C. elegans	5310	221	22437	3022	197	35143	8957	2612	120511
D. melanogaster	21921	641	16251	7023	266	21049	8957	2777	67893
H. sapiens	24065	4577	38213	8179	1221	29994	8957	3476	77288

Θ_SThe total number of observed interactions in species S
θ_SThe number of observed interactions in species S that contain an i Pfam domain pair
Ψ_SThe proteome size for species S
ψ_SThe number of proteins from species S that are seen in an interaction screen
χ_SThe number of i Pfam domain pairs observed in species S
${\hat{x}}_{S}$ The predicted total number of i Pfam domain pairs in species S
Ξ The total number of known Pfam domains
ζ_SThe number of Pfam domains observed in all protein of species S
$\hat{x}$ The estimated total number of i Pfam domains in all species
Prediction results are shown in bold font.

ISSN: 1471-2105