Figure 2

Cumulative cluster frequencies of CAC-containing motifs in human 3'-UTRs. Trends was used to determine the cumulative frequencies of clusters of 5–7 nucleotide long CAC-containing repeated motifs in the 'match' table (blue line) and 'match_random' table (red line). As can be seen, the frequencies of CAC-containing motifs with low P-values are much higher in real 3'-UTRs than they are in the shuffled ones. This type of separation is seen in all seven vertebrate species and with independently shuffled control data sets (data not shown).