Figure 4
Effect of SNP on PM and MM probe binding efficiency. The left panels show the perfect match (PM, in blue) and mismatch (MM, in green) whereas the right panels show another view of PM (top row) and MM (bottom row) values across the probes in the same probe-set 31568_at and for the same gene S10. Probe 9 (from left to right), SNP containing probe, is the probe of interest, highlighted in red bounding box. A) For the sample – CL2001032617AA, dChip output for the gene S10 shows better binding of probe 9 with PM [P9(PM) ] as compared to MM [P9(MM)]. B) For the sample – CL2001032008AA, dChip output for the gene S10 shows better binding of probe 9 with MM [P9(MM)] as compared to PM [P9(PM)].