Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model

Table 2 Mean number of mixture model components

Library	k	Unambiguous	Ambiguous	Significance
GSM31931	1	93	0	p < 2.2E-16 (χ² = 134.1; df = 4)
	2	405	15
	3	210	32
	4	27	12
	5	5	12
GSM31935	1	74	34	p = 1.8E-6 (χ² = 32.1; df = 4)
	2	317	246
	3	149	171
	4	17	30
	5	3	14

Expressed ambiguous and unambiguous 10 base pair tags for two LongSAGE libraries were distinguished based on the number of 17 base pair sequences that give rise to the same tag. The tags in each of these two groups were binned according to the number of estimated mixture components. The Chi-square statistic was used to test the null hypothesis that these two groups are equivalent.

ISSN: 1471-2105