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Table 3 Top component memberships

From: Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model

Dataset   
Component assignment Freq. p -value
BRAIN
astrocytoma (N = 14 nk = 2 = 454)
   -+------------ 14 4.3E-28
   ---+++++++++++ 12 2.7E-23
ependymoma (N = 10 nk = 2 = 544)
   -+-------- 16 6.0E-14
   --+------- 15 9.3E-13
glioblastoma (N = 7 nk = 2 = 607)
   ---+--- 48 3.2E-19
   -----+- 42 5.2E-15
medulloblastoma (N = 18 nk = 2 = 438)
   -----------------+ 4 1.5E-9
   -----------+-----+ 4 1.5E-9
normal (N = 9 nk = 2 = 588)
   -----+-- 41 7.4E-37
   -----+-+ 21 7.6E-14
AML
inv(16) (N = 5 nk = 2 = 387)
   -++++ 110 2.5E-39
   -+-++ 36 0.028
t(8;21) (N = 5 nk = 2 = 387)
   -++-- 110 2.5E-39
   -++-+ 36 0.028
t(15;17) (N = 5 nk = 2 = 225)
   -++-- 110 4.5E-67
   -++-+ 36 1.0E-6
t(9;11) de novo (N = 4 nk = 2 = 502)
   -+-+ 143 1.6E-16
   -+-- 132 1.4E-12
t(9;11) treated (N = 3 nk = 2 = 405)
   -++ 216 1.1E-16
BREAST
normal (N = 6 nk = 2 = 571)
   ---+-- 82 3.6E-29
   -----+ 65 4.0E-18
DCIS (N = 4 nk = 2 = 154)
   --++ 97 1.4E-43
   -+++ 41 4.5E-5
invasive (N = 3 nk = 2 = 765)
   -+- 337 4.6E-10
SKIN
normal (N = 4 nk = 2 = 500)
   ---+ 215 1.8E-54
melanoma (N = 3 nk = 2 = 650)
   -+- 405 2.1E-51
  1. For each set of biological replicates, the top one or two component states were selected from tags where the estimated number of components is 2. One component was represented with -, the other with + (i.e. -+- is equivalent to +-+). The significance was calculated using a zero-truncated Binomial test. The number of possible ways for the libraries to be assigned to the two components is (2N/2)-1, where N is the number of libraries.