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Table 4 Top 20 elements of the 441 ones of a window of size 21 according to the Fisher's index

From: Prediction of the burial status of transmembrane residues of helical membrane proteins

Rank

Position1

Type

Fisher's index

1

T

conservation index

0.987

2

C4

conservation index

0.534

3

N4

conservation index

0.469

4

N3

conservation index

0.307

5

N7

conservation index

0.306

6

C3

conservation index

0.248

7

T

L2

0.243

8

C7

conservation index

0.240

9

T

G

0.203

10

T

I

0.143

11

C8

conservation index

0.132

12

C1

conservation index

0.092

13

T

V

0.059

14

N1

conservation index

0.057

15

N4

I

0.057

16

N4

G

0.056

17

T

F

0.053

18

T

S

0.052

19

N8

conservation index

0.045

20

N4

L

0.041

  1. 1T: the target residue, C4: the 4th residue C terminal to the target residue, N4: the 4th residue N terminal to the target residue. Thus, the conservation index of the target residue is most indicative of its burial status, and the conservation index of the 4th residue C terminal to the target residue is second most indicative of the burial status of the target residue.
  2. 2L: leucine, G: glycine, I: isoleucine, V: valine, F: phenylalanine and S: serine.