Figure 2

Validation of the ASCA model for bromobenzene treated rats, validation of the dosage and the dosage-time interaction and the X _δ + X _τδ score plot. This experiment deals with the urine analysis of bromobenzene treated rats, the experimental design includes two types of controls and 3 dosage levels of the hepatotoxicant bromobenzene. The dosage and the interaction models are both significant as is clear from the reference distributions (p ≤ 0.0001). Because the dosage and the interaction models are significant they are superimposed and analyzed by SCA. The score plot of the SCA solution is shown. From this plot it is clear by visual inspection that the average dosage levels differ and that the interaction effect exists.