Skip to main content

Table 1 Test results of the 18 parameters implemented in miRFinder

From: MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans

Parameters Pre-miRNA Non-miRNA Hairpins Parameter Test
ID Symbol Mean Std. Deviation Mean Std. Deviation F value T test
01 pMFE -0.444 0.072 -0.218 0.086 1.44 0.000
02 pVMFE 0.455 0.936 0.506 0.632 0.03 0.014
03 pVStrc 0.903 1.812 3.635 4.703 0.41 0.000
04 pMatch 0.892 0.063 0.639 0.176 1.06 0.000
05 pDI 0.050 0.058 0.088 0.126 0.21 0.000
06 pMismatch 0.097 0.060 0.196 0.119 0.55 0.000
07 pBulge 0.014 0.036 0.169 0.209 0.64 0.000
08 pMutFreq 0.018 0.024 0.136 0.126 0.78 0.000
09 "=-" 0.043 0.029 0.035 0.031 0.13 0.000
10 "==" 0.649 0.081 0.466 0.089 1.08 0.000
11 "=:" 0.090 0.041 0.093 0.037 0.04 0.001
12 "--" 0.023 0.041 0.043 0.076 0.17 0.000
13 "-=" 0.043 0.029 0.035 0.031 0.13 0.000
14 "^^" 0.008 0.021 0.090 0.130 0.54 0.000
15 "^=" 0.014 0.018 0.044 0.026 0.69 0.000
16 "::" 0.044 0.044 0.102 0.086 0.45 0.000
17 ":^" 0.014 0.018 0.044 0.026 0.69 0.000
18 ":=" 0.076 0.041 0.048 0.037 0.36 0.000
  1. Note: T tests are 2-tailed. The F value represents the discriminative power of the parameters. The 18 parameters were coded as. 1: Minimum Free Energy; 2: The difference of the MFE of the sequence pair; 3: The difference of the structure of the sequence pair; 4–7: Base pairing and other properties of the 22 mer hypothesized mature miRNA; 8: The mutation frequency of the sequence segment pair; 9–18: The frequency of the 10 possible secondary structure elements (combinations of 2 adjacent characters) in the pseudo code of stem region (represented by the new syntax). [See details in additional file 1].