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Table 5 Comparison of RNAspa with RNAcast on contaminated datasets

From: RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules

Family

MCC

 

RNAspa

RNAcast

lin4

0.86

no data

tRNA

0.80

0.42

5S RNA

0.51

no data

U2

0.72

no data

S box riboswitch

0.77

0.82

SRP RNA

0.93

0.78

IRES

1.00

no data

Purine riboswitch

0.90

0.78

U1

0.61

no data

U12

0.83

no data

  1. Contaminated datasets were constructed by adding a single randomly picked sequence from a different family to each family tested. RNAspa was able to produce good results for all families while RNAcast was unable to find a consensus structure for six of the ten families in a contaminated dataset. See [Additional File 8] for raw data.
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BMC Bioinformatics

ISSN: 1471-2105

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