TY - JOUR AU - Berger, Seth I. AU - Posner, Jeremy M. AU - Ma'ayan, Avi PY - 2007 DA - 2007/10/04 TI - Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases JO - BMC Bioinformatics SP - 372 VL - 8 IS - 1 AB - In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from low-throughput experimental biomedical research literature, extracted automatically from literature using techniques such as natural language processing (NLP), generated experimentally using high-throughput methods such as yeast-2-hybrid screens, or interactions are predicted using an assortment of computational approaches. Genes or proteins identified as significantly changing in proteomic experiments, or identified as susceptibility disease genes in genomic studies, can be placed in the context of protein interaction networks in order to assign these genes and proteins to pathways and protein complexes. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-8-372 DO - 10.1186/1471-2105-8-372 ID - Berger2007 ER -