From: qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Organism | Km (mM)* | kcat (105 min-1) | kcat/Km (107 M-1s-1) | SwissProt ID Sequence identity to 1r2rA | Conditions, Reference |
---|---|---|---|---|---|
Trypanosoma brucei | 0.46 (0.25–0.46) | 3.1 (2.6–3.7) | 1.120 | TPIS_TRYBB 53% | 20°C, 100 mM, pH 7.4 [56] |
Trypanosoma cruzi | 0.45 | 2.7 | 1.000 | TPIS_TRYCR 53% | 20°C, 100 mM, pH 7.4 [57] |
Oryctolagus cuniculus muscle | 0.43 (0.32–0.43) | 1.86 (1.9–5.1) | 0.721 | TPIS_RABIT 100% | 30°C, 50 mM, pH 7.6 [56] |
Gallus gallus muscle | 0.47 | 2.56 | 0.915 | TPIS_CHICK 89% | 30°C, 100 mM, pH 7.4 [58] |
Saccharomyces cerevisiae | 1.22 (0.62–1.5) | 7.9 (1.4–10)) | 1.080 | TPIS_YEAST 52% | 25°C, 100 mM, pH 7.6 [59] |
Leishmania mexicana | 0.41 (0.30–0.41) | 2.52 (4.3–2.5) | 1.020 | TPIS_LEIME 52% | 25°C, 100 mM, pH 7.6 [60] |
Plasmodium falciparum | 0.35 | 2.68 | 1.280 | TPIS_PLAFA 42% | 30°C, 50 mM, pH 7.9 [56] |
Vibrio marinus | 1.9 | 4.2 | 0.368 (0.515)# | TPIS_VIBMA 41% | 10°C, 100 mM, pH 7.6 [61] |
Escherichia coli | 1.03 | 5.4 | 0.874 | TPIS_ECOLI 45% | 25°C, 100 mM, pH 7.6 [61] |
Homo Sapiens | 0.49 | 2.7 | 0.918 | TPIS_HUMAN 98% | 25°C, 100 mM, pH 7.6 [62] |
Giardia lamblia | 0.53 | 2.9 | 0.912 | TPI1_GIALA 45% | 25°C, 100 mM, pH 7.4 [63] |
Spinacia oleracea | 0.68 | 2.7 | 0.662 | TPIC_SPIOL 60% | 25°C, 100 mM, pH 7.5 [64] |