Figure 5From: Single TNFα trimers mediating NF-κ B activation: stochastic robustness of NF-κ B signalingCharacteristics of cell activation as a function of dose. Panel A: Probability of cell activation (at least one receptor activation) for 10 min. stimulation as a function of TNFα dose. Panel B: Cell activity measured as an average height of the IKKKa, IKKa, nuclear NF-κ B, and A20mRNA peak resulting from 10 min. activity of 1, 3, 10, 30, or 100 receptors.Back to article page