Figure 6
From: Single TNFα trimers mediating NF-κ B activation: stochastic robustness of NF-κ B signaling
Model predictions for pulse low dose TNFα stimulation. Panel A: Probability of cell activation during 5 min. long TNFα stimulation as a function of dose, model prediction (red) versus threshold hypothesis: green (3 receptors), black (10 receptors). Panel B: Average height of nuclear NF-κ B peak calculated for subpopulation of N = 500 of activated cells (at least with one receptor activated) after 5 min. long TNFα stimulation as a function of TNFα dose.