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Table 4 Fold change in expression of genes in LexA regulon due to MX treatment and normalized to control

From: Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of MX-treated Salmonella

  

μM MX

Gene

p-value*

0.25

0.5

1

  

3.2

5.8

8.6

STM2727

0.00003

5.5

11.1

14.8

dinP

0.00003

3.7

4.8

4.8

sulA

0.00004

4.4

7.6

12.6

umuD

0.00004

5.2

8.3

14.3

STM1019

0.00005

4.8

8.4

8.9

dinI

0.00016

8.7

14

16.9

yebG

0.00019

5.5

8.8

13.5

lexA

0.00035

2.9

3.5

4

STM1309

0.00102

-1.3

1.9

2.5

polB

0.00103

2.3

3.1

2.8

yigN

0.00118

2.2

2.7

3

uvrA

0.00129

1.7

2.1

2.5

recA

0.00219

4

6.3

7.8

uvrD

0.00241

1.4

1.8

2.2

ruvA

0.00366

1.7

2.3

2.2

sbmC

0.00612

4.1

7.2

7.4

ydjM

0.00629

1.6

1.9

2.2

recN

0.02699

8

11.4

16

yehR

0.05804

1.1

0.8

9.6

ftsK

0.18374

1.3

1.2

1.4

STM1056

0.20943

0.9

1.3

1.5

dinG

0.4182

1

0.7

1.2

uvrB

0.43548

3.7

0.7

1.3

minC

0.46889

1

1

0.9

mfd

0.7057

0.9

1

0.9

ftsY

0.70953

1

1.1

1.1

ybfE

0.80643

0.1

0.9

0.9

recG

0.91485

1

0.9

1

STM0925

0.97301

1

0.9

1

STM2621

No Data

   

ssb

No Data

   

yjiW

 

1.8

1.4

1.9

  1. *The p-value was determined by a Cyber-T t-test of control to the high concentration of MX.