Table 5 Augmentation of differentially expressed genes in KEGG pathways by addition of operon and monotonic analyses to CyberT analysis
| Â | CyberT | CyberT + operon + monotonic | ||
|---|---|---|---|---|
KEGG Pathway* | No. genes | p-value | No. genes | p-value |
Porphyrin metabolism | 2 | 0.230 | 19 | 4.75 × 10-9 |
Flagellar assembly | 7 | 0.027 | 15 | 3.27 × 10-5 |
Type III secretion system | 4 | 0.132 | 12 | 8.35 × 10-5 |
Sulfur metabolism | 6 | 0.0002 | 7 | 0.0002 |
Thiamine metabolism | 1 | 0.382 | 6 | 0.003 |
Nitrogen metabolism | 0 | NA | 1 | 0.004 |
Biosynthesis of siderophore group peptides | 1 | 0.338 | 4 | 0.005 |
Pyruvate metabolism | 0 | NA | 1 | 0.008 |
Two-component system | 0 | NA | 1 | 0.010 |
ABC transporters, prokaryotic | 11 | 0.120 | 27 | 0.011 |
Selenoamino acid metabolism | 5 | 0.010 | 6 | 0.014 |
Oxidative phosphorylation | 0 | NA | 1 | 0.018 |
Other ion-coupled transporters | 2 | 0.013 | 6 | 0.035 |
Ascorbate and aldarate metabolism | 1 | 0.338 | 3 | 0.035 |
Arginine and proline metabolism | 0 | NA | 1 | 0.037 |
HTH family transcriptional regulators | 1 | 0.072 | 2 | 0.043 |