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Table 1 Genes used in model construction.

From: Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data

Gene Symbol Accession Number GeneID Gene Description Function
GPC3 NM_004484 2719 glypican 3 Cell surface heparan sulfate proteoglycans; may play a role in the control of cell division and growth regulation
RASSF1A NM_007182 11186 Ras association domain family 1 Protein similar to the RAS effector proteins; interact with DNA repair protein XPA; inhibit cyclin D1 accumulation thereby inducing cell cycle arrest
WT1 NM_000378 7490 Wilms tumor 1 A transcription factor; mutated in a small subset of patients with Wilm's tumours
PLAU NM_002658 5328 plasminogen activator, urokinase A serine protease involved in degradation of the extracellular matrix.
HOXA5 NM_019102 3202 homeobox A DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
CDKN2A NM_000077 1029 cyclin-dependent kniase inhibitor 2A Functions as a stabilizer of the tumor suppressor protein p53.
HS3ST3B1 NM_006041 9953 heparan sulfate 3-O-sulfotransferase 3B1 An enzyme that possesses heparan sulfate glu-cosaminyl 3-O-sulfotransferase activity
BRCA1 NM_007294 672 breast cancer 1, early onset A nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor
DAPK1 NM_004938 1612 death-associated protein kinase 1 A positive mediator of gamma-interferon induced programmed cell death