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Figure 1 | BMC Bioinformatics

Figure 1

From: Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on Boolean network modeling

Figure 1

Correlation between the functional importance of proteins and the NuFBL. (a) The NuFBL's were plotted against the mutant phenotypes of the proteins in the network where proteins were classified according to the previous report [1]. (b) The NuFBL's were plotted against the evolutionary rate [1] (dN/dS) of proteins which were grouped into five different classes according to their evolutionary rates. For each protein group, the average and the confidence interval for 95% confidence level of the NuFBL are shown on the y-axis (see additional data file 4 for further details).

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