Predicting zinc binding at the proteome level

BMC Bioinformatics

Table 2 Amino acid statistics on zinc sites

Site type	Zn4			Zn3			Zn2			Zn1			All
Amino acid	N _a	f _a	f _s	N _a	f _a	f _s	N _a	f _a	f _s	N _a	f _a	f _s	N _a
C	663	69.3	91.8	45	12.2	6.2	10	7.7	1.4	4	10.8	0.6	722
H	220	23.0	45.7	194	52.6	40.3	59	45.4	12.3	8	21.6	1.7	481
D	48	5.0	27.6	83	22.5	47.7	30	23.1	17.2	13	35.1	7.5	174
E	18	1.9	17.5	46	12.5	44.7	28	21.5	27.2	11	29.7	10.7	103
N	5	0.5	83.3	0	0.0	0.0	1	0.8	16.7	0	0.0	0.0	6
Q	2	0.2	33.3	1	0.3	16.7	2	1.5	33.3	1	2.7	16.7	6
Total	956	100	-	369	100	-	130	100	-	37	100	-	1492

Statistics over the 305 zinc chains (464 binding sites) divided by amino acid and site type. N_ais the amino acid occurrence number in corresponding site type; f_ais the observed percentage of each amino acid in a given site type; f_sis the observed percentage of each site type for a given amino acid. All is the total number of times a given amino acid binds zinc in general.

ISSN: 1471-2105