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Figure 1 | BMC Bioinformatics

Figure 1

From: On the detection of functionally coherent groups of protein domains with an extension to protein annotation

Figure 1

An illustration of the derivation of a DASSEM unit and its functional annotation. For the group of proteins shown, there are three prevalent domain compositions within individual proteins (circled). The domain fusions of these prevalent domain compositions were used to link three domains and to create a DASSEM unit that contains the fork head (FH) domain, the fork head associated (FHA) domain and the kinase domain. The overall function of the DASSEM unit was obtained by finding the GO terms that were enriched across the proteins associated with the unit. The GO term enrichment indicated that the unit participates in the cell cycle. Schematics of domains and proteins were taken from the Pfam database [89].

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BMC Bioinformatics

ISSN: 1471-2105

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