Skip to main content

Advertisement

Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Table 1 Superdomains detected by our method from MIPS protein interaction data, where GO annotations are denoted in italic

From: Analysis on multi-domain cooperation for predicting protein-protein interactions

Superdomains Descriptions GO similarity
PF00488, PF05192 (1) MutS domain V, ATP binding, damaged DNA binding, mismatch repair
(2) MutS domain III, DNA metabolism
2-1-2-5-11-27-1-8-10
2-1-2-5-11-27-1
Similarity: 7
PF02775, PF00205 (1) Thiamine pyrophosphate enzyme, C-terminal TPP binding domain, catalytic activity, thiamin pyrophosphate binding
(2) Thiamine pyrophosphate enzyme, central domain, magnesium ion binding, thiamin pyrophosphate binding
1-1-2-12-1-8
1-1-2-12-1-8
Similarity: 6
PF08033, PF04810 (1) Sec23/Sec24 beta-sandwich domain
(2) Sec23/Sec24 zinc finger, COPII vesicle coat, protein binding, intracellular protein transport, ER to Golgi vesicle-mediated transport
 
PF03953, PF00091 (1) Tubulin/FtsZ family, C-terminal domain, protein complex, GTP binding, GTPase activity, protein polymerization
(2) Tubulin/FtsZ family, GTPase domain
 
PF07687, PF01546 (1) Peptidase dimerisation domain, hydrolase activity, protein dimerization activity
(2) Peptidase family M20/M25/M40, metallopeptidase activity, proteolysis
1-1-3-16
1-1-3-16-18-6
Similarity: 4
PF05000, PF00623 (1) RNA polymerase Rpb1, domain 4, DNA-directed RNA polymerase activity, DNA binding, transcription
(2) RNA polymerase Rpb1, domain 2, nucleus, DNA-directed RNA polymerase activity, DNA binding, transcription
1-1-3-39-16-3-16
1-1-3-39-16-3-16
Similarity: 7
PF08544, PF00288 (1) GHMP kinases C terminal
(2) GHMP kinases N terminal domain, ATP binding, kinase activity, phosphorylation
 
PF01798, PF08060 (1) Putative snoRNA binding domain
(2) NOSIC (NUC001) domain
 
PF02800, PF00044 (1) Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, NAD binding, glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity, glycolysis
(2) Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain, NAD binding, glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity, glycolysis
2-1-2-5-11-1-4-9-1-5-1
2-1-2-5-11-1-4-9-1-5-1
Similarity: 11
PF08030, PF08022 (1) Ferric reductase NAD binding domain
(2) FAD-binding domain