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Table 6 The overlap of the predicted domain interactions by APMM and LPM with those in iPfam, where λ denotes domain interaction probability, 'Single organism' means the training set of protein interactions is only from yeast, 'Multiple organisms' means the training set is from three organisms: yeast, worm and fly

From: Analysis on multi-domain cooperation for predicting protein-protein interactions

Thresholds

Single organism (p-value)

Multiple Organisms (p-value)

APMM

  

λ > 0.1

110 (8.1e-009)

256 (8.4e-012)

λ > 0.2

99 (< 1e-013)

202 (2.9e-011)

λ > 0.3

61 (9.8e-010)

149 (< 1e-013)

λ > 0.4

52 (3.2e-010)

127 (8.1-013)

λ > 0.5

49 (1.5e-013)

91 (3.3e-012)

LPM

  

λ > 0.1

109 (2.1e-008)

256 (5.7e-013)

λ > 0.2

97 (8.8e-013

201 (5.9e-013)

λ > 0.3

61 (< 1e-013)

148(2.9e-012)

λ > 0.4

54 (4.4e-011)

130 (< 1e-013)

λ > 0.5

49 (< 1e-013)

93 (< 1e-013)