Skip to main content

Table 6 The overlap of the predicted domain interactions by APMM and LPM with those in iPfam, where λ denotes domain interaction probability, 'Single organism' means the training set of protein interactions is only from yeast, 'Multiple organisms' means the training set is from three organisms: yeast, worm and fly

From: Analysis on multi-domain cooperation for predicting protein-protein interactions

Thresholds Single organism (p-value) Multiple Organisms (p-value)
APMM   
λ > 0.1 110 (8.1e-009) 256 (8.4e-012)
λ > 0.2 99 (< 1e-013) 202 (2.9e-011)
λ > 0.3 61 (9.8e-010) 149 (< 1e-013)
λ > 0.4 52 (3.2e-010) 127 (8.1-013)
λ > 0.5 49 (1.5e-013) 91 (3.3e-012)
LPM   
λ > 0.1 109 (2.1e-008) 256 (5.7e-013)
λ > 0.2 97 (8.8e-013 201 (5.9e-013)
λ > 0.3 61 (< 1e-013) 148(2.9e-012)
λ > 0.4 54 (4.4e-011) 130 (< 1e-013)
λ > 0.5 49 (< 1e-013) 93 (< 1e-013)