Table 2 Comparison of methods used in the three gene prioritization applications
From: Improved human disease candidate gene prioritization using mouse phenotype
Data type | SUSPECTS | ENDEAVOUR | ToppGene |
|---|---|---|---|
Attribute-based data | Semantic similarity | p-value from meta-analysis | Fuzzy measure based similarity |
Vector-based data | Pearson correlation | Pearson correlation | Pearson correlation |
Combination of scores | Weighted mean | p-value from order statistics | p-value from meta-analysis |