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Table 4 Performance summary of locus-region cross-validation using different feature sets. When either MP or PubMed, or both (MP + PubMed) were left out, the performance dropped significantly

From: Improved human disease candidate gene prioritization using mouse phenotype

Features

Average rank ratio of "target" genes

Number of times "target" genes were ranked top 5%

Number of times "target" genes were ranked top 10%

All

7.39%

118

125

GO + MP + PubMed

7.50%

118

126

MP + PubMed

7.08%

121

126

Without GO

6.84%

117

123

Without Pathway

7.66%

118

124

Without Domain

6.71%

118

124

Without Interaction

7.17%

120

124

Without Expression

7.28%

118

128

Without MP

9.77%

110

117

Without Pubmed

9.91%

100

111

Without MP & Pubmed

22.61%

71

80