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Figure 5 | BMC Bioinformatics

Figure 5

From: Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study analyzing the neurotransmitter/Na+ symporter family

Figure 5

Structural descriptions of the functional site predictions within the leucine (top) and sodium ion (bottom) binding sites. Red indicates functional residues that are predicted, whereas blue indicates not predicted by (a) phylogenetic motifs, (b) false positive expectation, (c) site conservation, (d) Rate4Site, (e) evolutionary trace, and (f) SDPpred. (g) In the last frame, residues are color-coded based on the number of methods (excluding SDPpred) that predict each position (0 = blue, 1 = cyan, 2 = green, 3 = yellow, 4 = red, and 5 = magenta). In all cases, the leucine and sodium ion substrates are colored orange.

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BMC Bioinformatics

ISSN: 1471-2105

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