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Table 2 MIPS functional distribution of gene representative clusters

From: Growing functional modules from a seed protein via integration of protein interaction and gene expression data

Cluster/Genes Functional distribution (MIPS) Percentage (fraction of genes) p-value
1/n = 376 14 protein fate 27.2% (102) 2.64 e-05
  14.07 protein modification 17% (64) 1.03 e-05
  11.02.03 mRNA synthesis 15.2% (57) 1.35 e-04
4/n = 259 11 transcription 29.7% (77) 6.45 e-07
  10.03 cell cycle 19.3% (50) 1.58 e-05
  10.03.01 mitotic cell cycle and cell cycle control 12.7% (33) 9.93 e-04
7/n = 189 42 biogenesis of cellular components 21.6% (41) 2.47 e-03
  14.07 protein modification 16.4% (31) 3.91 e-03
  11.01.03 mRNA processing 9% (17) 5.22 e-05
16/n = 82 16 protein with binding function or cofactor requirement 32.9% (27) 3.31 e-04
  43.01 fungal/microorganismic cell type differentiation 18.2% (15) 8.20 e-04
  43.01.03 fungal and other eukaryotic cell type differentiation 18.2% (15) 8.20 e-04
3/n = 183 01 metabolism 30% (55) 5.48 e-02
  10.03 cell cycle 14% (26) 7.48 e-02
  11.04.03 mRNA processing 8% (13) 3.57 e-03
6/n = 181 01 metabolism 39.7% (72) 3.91 e-06
  10.01 DNA processing 15.4% (28) 1.05 e-03
  11.02.03 mRNA synthesis 17.6% (32) 2.99 e-04
  1. Examples of gene clusters after clustering the gene expression data. The first column represents the number of cluster and the number of genes in it. The second column represents the functional distribution of every cluster according to MIPS from the main category up to the third-level subcategory. The third column shows the percentage of genes belonging to this category and in the brackets the corresponding actual number. The last column displays the p-value found by MIPS in every functional category.