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Table 2 Categories evolving fast in humans and chimpanzees

From: FUNC: a package for detecting significant associations between gene sets and ontological annotations

GO ID

Category

Genesa

AA rod.b

AA prim.c

Ratiod

GO:0003674

molecular_functione

4303

84306

8604

0.1

GO:0004889

nicotinic acetylcholine-activated cation-selective channel activity

6

85

29

0.34

GO:0004984

olfactory receptor activity

5

78

32

0.41

GO:0005184

neuropeptide hormone activity

13

95

31

0.33

GO:0005217

intracellular ligand-gated ion channel activity

2

117

30

0.26

GO:0005272

sodium channel activity

9

124

34

0.27

GO:0005279

amino acid-polyamine transporter activity

19

276

63

0.23

GO:0005523

tropomyosin binding

4

14

12

0.86

GO:0008188

neuropeptide receptor activity

17

212

44

0.21

GO:0008271

sulphate porter activity

4

107

37

0.35

GO:0015194

L-serine transporter activity

1

7

8

1.14

GO:0016652

oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor

10

140

36

0.26

GO:0031402

sodium ion binding

31

684

109

0.16

GO:0031404

chloride ion binding

26

459

79

0.17

  1. a number of genes analysed in category; b number of amino acid changes between mouse and rat; b number of amino acid changes between human and chimpanzee; b number of amino acid changes between mouse and rat; dratio of primates/rodents; ethe ratio in the top category, in this case molecular function, gives the expected ratio.