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Table 5 FGA-generated feature set show significant overlap with ESE and ESS regulator signal sets.

From: Features generated for computational splice-site prediction correspond to functional elements

FGAset size AstESR (285) RescueESE (238) ChPESE (1701) FasESS (176) ChPESS (924)
   Overlap, P-value Overlap, P-value Overlap, P-value Overlap, P-value Overlap, P-value
A-3mer3 [1,80] 313 34 0.00514 24 0.09415 175 2.09e-06 10 0.877 73 0.5407
A-3mer3 [1,80]+ 177 28 0.00003 24 0.00007 130 1.42e-18 1 0.999 8 *
A-3mer3 [1,80]- 136 6 0.92089 0 * 43 0.9939 9 0.129 59 3.19e-08
A-4mer2 [1,80] 317 35 0.00347 26 0.04319 177 1.96e-06 10 0.887 72 0.6423
A-4mer2 [1,80]+ 179 29 0.00001 25 0.00003 129 2.74e-17 1 0.999 9 *
A-4mer2 [1,80]- 138 6 0.92714 1 0.99999 46 0.9819 9 0.137 57 4.22e-07
A-5mer1 [1,80] 342 35 0.01147 27 0.05920 278 1.06e-08 12 0.812 70 0.9300
A-5mer1 [1,80]+ 187 29 0.00003 25 0.00006 134 1.40e-17 3 0.999 9 *
A-5mer1 [1,80]- 155 6 0.96496 2 0.99915 59 0.8352 9 0.221 54 0.000257
A-6mer [1,80] 465 54 0.00006 27 0.53401 278 1.06e-08 17 0.799 91 0.9993
A-6mer [1,80]+ 263 38 0.00001 25 0.00899 165 6.61e-13 7 0.943 19 *
A-6mer [1,80]- 202 16 0.32994 2 0.99984 76 0.8907 10 0.368 64 0.001374
D-5mer1 [-80,-1] 64 10 0.01195 32 1.32e-23 60 5.59e-19 1 0.941 4 0.9999
D-5mer1 [-80,-1]+ 56 9 0.01403 30 2.47e-23 52 4.27e-16 0 * 4 0.9995
D-6mer [-80,-1] 1052 126 1.44e-12 112 1.81e-13 613 3.73e-37 26 0.999 183 0.9999
D-6mer [-80,-1]+ 701 93 2.28e-11 109 6.16e-28 482 1.02e-57 6 0.999 63 *
D-6mer [-80,-1]- 271 20 0.42504 1 0.99999 90 0.9985 19 0.022 106 1.54e-10
  1. * p-value is very close to 1.
  2. The number of shared features between the FGA generated sets of hexamers and the exon regulator hexamer sets and the p-value stating the probability of having this overlap or a greater overlap by chance. We highlight the highly statistically significant probabilities. The set D -3mer 3 [-80,-1] did not contain position specific hexamers and the set D -4mer 2 [-80,-1] contained only 3 position specific hexamers, two of which overlapped with RescueESE set.