Skip to main content

Table 2 Accuracy and coverage in three integrated methods

From: InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic genomes

  

KEGG

EcoCyc

DIP

 

Number of PPIs

Accuracy (%)

Coverage (%)

Accuracy (%)

Coverage (%)

Accuracy (%)

Coverage (%)

Joint observation method (JOM)

JOM4a

55

78.18

0.10

32.73

2.65

25.45

0.44

JOM≥3

298

60.74

0.41

32.89

14.45

12.42

1.17

JOM≥2

2,933

38.70

2.58

9.00

38.94

2.35

2.18

JOM≥1

54,911

8.79

10.98

0.85

69.17

0.49

8.58

STRING

Highb

2,279

24.62

1.28

13.43

42.33

3.20

2.31

Medium

4,458

5.74

0.58

1.39

7.08

0.31

0.44

Low

9,970

2.18

0.49

0.17

2.21

0.11

0.35

InPrePPI

Highc

1,194

45.73

1.24

18.84

33.19

4.69

1.77

Medium

5,403

27.93

3.43

2.24

17.85

0.91

1.55

Low

48,314

5.73

6.30

0.25

18.14

0.34

5.25

  1. aThe predicted PPIs covered by at least one (JOM≥1), two (JOM≥2), three (JOM≥3) or four (JOM4) methods.
  2. bThe predicted PPIs in the high, medium and low confidence in STRING [22].
  3. cThe predicted PPIs in the high, medium and low confidence in InPrePPI (see Methods).