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Figure 1 | BMC Bioinformatics

Figure 1

From: DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis

Figure 1

The cross-reference among different types of gene identifiers is improved by the DAVID Gene Concept. A. As global examples, four popular types of protein identifiers (PIR ID, UniProt Accession, RefSeq Protein, and GenPept Accession) are only cross-referenced partially by NCBI Entrez Gene (EG), UniProt UniRef100 (UP), and PIR NRef100 (NF). B. The DAVID Gene Concept, a single-linkage algorithm, iteratively agglomerates all types of gene IDs, belonging to the same gene entry, for example, ubiquitin specific peptidase 8 (USP8), into one DAVID gene cluster (ID 2859041). Such integration makes the cross-reference of different types of gene IDs more comprehensive than that in each of the original databases, particularly for the IDs across NCBI and UniProt systems.

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BMC Bioinformatics

ISSN: 1471-2105

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