Figure 2

An artificial stimulon. This screenshot shows the improved network analysis and visualization feature GraphVis. Presented is the artificial stimulon of table 2 projected onto the underlying gene regulatory network. The nodes represent genes and the edges gene regulations. Red nodes are repressors, green nodes activators, and blue nodes dual regulators. Gray nodes are target genes. A red edge represents a repression, a green edge an activation, and a blue edge a sigma factor regulation. The nodes sizes are relative to the expression value (M-value): the bigger the node, the more the differential expression of the respective gene. Genes can be upstimulated (green dotted node border) or downstimulated (red dotted border). The big multi-node groups genes to an operon. The circular node inside the operon is that gene, which is preceded by a transcription factor binding site.