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Table 2 Estimation of the mixture proportion

From: A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays

 

Estimated mixture

Accuracy (%)

True mixture

Average

Stdev

Without mixture

With mixture

0.60

0.603

0.012

90.31

95.45

0.70

0.719

0.069

94.43

96.16

0.80

0.803

0.009

96.87

97.52

0.90

0.902

0.014

98.16

98.25

  1. Simulated data sets were created based on the analyses of the bladder tumour samples. Here the average is calculated for all samples where the amount of informative SNPs (states 1 to 5) was suffciently high (> 5%, see Methods). The number of correctly identified states is shown with and without estimation of the mixture proportion.
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BMC Bioinformatics

ISSN: 1471-2105

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