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Table 2 Estimation of the mixture proportion

From: A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays

  Estimated mixture Accuracy (%)
True mixture Average Stdev Without mixture With mixture
0.60 0.603 0.012 90.31 95.45
0.70 0.719 0.069 94.43 96.16
0.80 0.803 0.009 96.87 97.52
0.90 0.902 0.014 98.16 98.25
  1. Simulated data sets were created based on the analyses of the bladder tumour samples. Here the average is calculated for all samples where the amount of informative SNPs (states 1 to 5) was suffciently high (> 5%, see Methods). The number of correctly identified states is shown with and without estimation of the mixture proportion.