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Table 1 High-confidence TF pairs verified in the literature.

From: Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining

TF pair Gene Regulated Source
Ap-2, p300 Mouse CITED4 [83]
Sp1, Gata2 Human PDGFβ receptor [84]
Sp1, p300 Human ERK1 [126]
Ap-2, Egr1 Human tumor necrosis factor α, rat chromogranin B, human PNMT [41–43, 67]
Ap-2, NFκB Human tumor necrosis factor α [41]
Egr1, Elk1 Human tumor necrosis factor α [41, 132]
Egr1, Nf1 Human tissue factor pathway inhibitor 2 [40]
Egr1, p300 Human tumor necrosis factor α [67]
Egr1, Sp1 Human TFPI-2, human SOD, human cd95, human TNFα [40, 74, 97, 132]
Sp1, p53 Human Icam1 [44, 45]
Mzf1, Sp1 Human N-cadherin [115]
Sp1, Srebp Porcine LDL receptor, rat FAS [123, 128]
Usf, Sp1 Rat FAS, human Top3, human liver fructose1,6 biphosphatase [101, 119, 123]
Aml1, NFκB Human GM-CSF [66]
Aml1, Srebp Human fatty acid synthase [64]
Elk1, p300 Human tumor necrosis factor α [132]
Gata2, NFκB Human erythropoietin [112]
Gata2, Sp1 Human PDGF receptor [84]
Nf1, NFκB Human tissue factor pathway inhibitor 2 [40]
NFκB, p300 Human I-gamma 1, mouse tapasin [87, 111]
Pax5, p300 Human immunoglobin κ [133]
Ap-1, NFκB Human interleukin 6, human RANTES, human TNFα, human GM-CSF [41, 60, 70, 77]
  1. Examples of high-confidence TF pairs that could be verified in the literature as co-regulators of mammalian genes.