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Table 2 Observed agreement and p-value for each pairwise comparison within each platform using the weighted kappa statistic. Print-tip loess normalized Cy5 intensities were used for both two-channel arrays; MAS5.0 expression summaries were used for Affymetrix GeneChips.

From: Application of a correlation correction factor in a microarray cross-platform reproducibility study

Chips compared

Observed Agreement

P-value

GMU

  

   1420 v 1421

71.89%

< 0.0001

   1420 v 1422

66.31%

< 0.0001

   1421 v 1422

75.41%

< 0.0001

C3B

  

   7–7 v 8–22

28.18%

1.00

   7–7 v 8–31

51.82%

< 0.0001

   8–22 v 8–31

29.14%

1.00

Affymetrix

  

   QAQC8 v QAQC10

89.75%

< 0.0001

   QAQC8 v QAQC13

89.54%

< 0.0001

   QAQC10 v QAQC13

89.57%

< 0.0001