Table 3 Independent design meta analysis of case-control studies, 1 null scenario. 2
From: PedGenie: meta genetic association testing in mixed family and case-control designs
Description | CMH Chi Square | CMH Chi-Square Trend | Meta Odds Ratio | |
|---|---|---|---|---|
| Â | Â | Â | Aa vs. AA | aa vs. AA |
Statistic, PedGenie 2.1 | 0.06 | 0.05 | 1.02 | 0.99 |
Empirical p-value, mean (SD) | 0.970 (0.005) | 0.829 (0.012) | 0.818 (0.031) | 0.967 (0.028) |
Empirical 95% CI: lower (SD) | Â | Â | 0.85 (0.007) | 0.49 (0.016) |
Empirical 95% CI: upper (SD) | Â | Â | 1.24 (0.010) | 2.00 (0.068) |
Statistic, SAS® | 0.06 | 0.05 | 1.02 | 0.99 |
Standard p-value | 0.972 | 0.830 | 0.816 | 0.971 |
Standard 95% CI: lower | Â | Â | 0.85 | 0.50 |
Standard 95% CI: upper | Â | Â | 1.23 | 1.96 |