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Figure 4 | BMC Bioinformatics

Figure 4

From: Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Kinase 2

Figure 4

Entropy Compensation in CDK2. An example of entropy compensation in CDK2 serving as a possible mechanism for protein allostery. The transitional changes from a semi-active to active state (dashed line) and finally from an active state to substrate bound state (solid line) are shown. The changes in fluctuation between the (a) G-loop and (b) T-loop are observed to have an inverse relationship with each other.

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BMC Bioinformatics

ISSN: 1471-2105

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