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Table 1 List of regulatory motif gene sets significantly enriched in individual functional clusters

From: Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis

Dataset

Functional cluster

Transcription factora

Myogenesis

1

Sp-1

 

2

Arnt, SREBP-1, Sp-1, MyoD, E2A, USF

 

3

Sp-1, USF, LBP-1, Myc

 

4

NRF-1, E2F, ATF/CREB, ETF, NF-Y, GABP, Elk-1, ZF5

Erythropoiesis

1

SREBP-1, USF, GATA-1

 

2

AP1

 

3

NF-Y, NRF-1, ATF/CREB, E2F, Arnt, Tel-2, Egr-3, Myc, ETF, Sp-1, GABP, YY1, HIF-1, Elk-1, ZF5

  1. aSignificantly enriched (P < 0.05, Bonferonni corrected) regulatory motif gene sets are shown for the corresponding transcription factors. When more than one regulatory motif sets corresponding to a single transcription factor were identified, the most significant one was listed taking the redundancy of regulatory motif gene sets into consideration. The listing order of transcription factors is according to the significance level of enrichment in individual functional clusters.