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Table 2 List of putative synergistic motif pairs

From: Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis

Dataset

Motif 1 (gene size/EC)a

Motif 2 (gene size/EC)

Gene sizeb

EC

Significancec

Myogenesis

Arnt (694/0.0020)

SREBP-1 (839/0.0024)

382

0.0086

0.02

 

Sp-1 (3178/0.0006)

MyoD (696/0.0082)

318

0.0201

< 0.01

 

Sp-1 (3178/0.0006)

E2A (906/0.0050)

444

0.0043

< 0.01

Erythropoiesis

SREBP-1 (1126/0.0171)

USF (372/0.0053)

839

0.0348

< 0.01

  1. aTwo regulatory motif gene sets are demonstrated as motif 1 and motif 2 with the gene numbers and expression coherence (EC) of the corresponding gene set. For motifs pairs, genes occurred both in two regulatory motif gene sets are separately measured for gene numberb and expression coherence. The significance levelc determined by permutation tests is also demonstrated. Only the motif pairs with significant expression coherence (P < 0.05) are shown in the list.