Figure 4

The Gap curves for four of the examined transcription factors (TFs). Shown is the distance between the observed R²(goodness) of the predicted regulon and the 95^th percentile of the null-distribution (which is not shown here). A positive R² means that the regulon is significant on the 5% significance level and the maximum of the Gap curve indicate the best number of genes to include in the regulon. The Gap curves for CBF, NAC072 and AREB are plotted along with the the curves obtained for two-hundred shuffled TFs (thin lines). The shuffled TFs get mostly negative Gap statistics as they lie close the expectation value of the null-distribution. CBF, NAC072 and AREB show very significant Gap curves, the HY5 regulon on the other hand does not.