Figure 2

Probe set off-target sensitivity and expression correlation. Boxplots depicting the expression correlation coefficients, ρ _XY stratified by off-target sensitivity score, $Q_{XY}^{75}$. Figures A and C show the data for all probe set pairs; for Figures B and D gene pairs with a BLAST hit in at least one direction with an E-value smaller than 10^-10 were omitted. A-B) Results obtained with Affymetrix' CDF. C-D) Results obtained with the custom-made CDF. The widths of the boxes are proportional to the number of observations in each group. ρ _XY was calculated on the tissue microarray dataset. The plots show results for all pairs with $Q_{XY}^{75}$ ≥ 55.